Ketamine Liquid 500mg

If sniffed the effects of ketamine generally come on quickly and can last from about 20 minutes to a couple of hours.

Why is Ketamine Liquid Used Medically?

• Ketamine liquid can provide pain relief and short-term memory loss (for example, amnesia of a medical procedure).
• In surgery, it is used an induction and maintenance agent for sedation and to provide general anesthesia.
• It has also been used for pain control in burn therapy, battlefield injuries, and in children who cannot use other anesthetics due to side effects or allergies.
• Ketamine, through blocking at the N-methyl-D-aspartate (NMDA) site, has rapid action in controlling symptoms of depression and acute suicidal ideation.
• At normal doses, it is often preferred as an anesthetic in patients at risk of bronchospasm and respiratory depression.

Pharmacology

Ketamine liquid is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, and it blocks HCN1 receptors. However, at higher doses it may also bind to the opioid mu and sigma receptors. It disrupts the neurotransmitter (brain chemical) glutamate. Glutamate is involved with learning, memory, emotion, and pain recognition. It can exhibit sympathomimetic activity which can lead to rapid heart rate and elevated blood pressure.

It is related to phencyclidine (PCP), but has less than 10% of the potency of pure PCP.

This agent is a lipid soluble compound, has an initial rapid distribution and large volume of distribution, with a half-life of 10 to 15 minutes. Secondarily, the drug distributes into peripheral tissues with a slower elimination half-life of up to 3 hours, undergoes hepatic metabolism and is excreted in the urine.Liquid LSD

How is Ketamine Abused?

In addition to its legal, medical uses, ketamine and and synthesized analogs have become drugs of abuse with hallucinogenic properties. It has also been used as a “date rape” drug.

When abused, it is typically insufflated (“snorted” up the nose) in social situations. It is also injected, consumed orally as a liquid, or smoked in marijuana or tobacco. It is frequently abused in combination with other substances, such as cocaine or amphetamines. Use with multiple drugs has been fatal.Adderall XR

When misused, it is often sourced via the illegal diversion of prescription products, but analogs may be found on the streets. Ketamine Liquid 500mg

How Quickly Does it Work?

• An injection yields a quick response, with effects occurring in seconds to minutes.
• “Snorting” leads to effects in roughly 5 to 15 minutes (this is the most common method of abuse).
• Oral consumption requires between 5 and 30 minutes.

The effects of abuse typically last 1 to 2 hours, but the users judgement, senses and coordination may be affected for up to 24 hours or longer. Sensations the user may seek include floating, stimulation and visual effects.

High doses may dangerously reduce breathing, lead to muscle spasms or weakness, dizziness, balance difficulty, impaired vision, slurred speech, nausea and vomiting, and severe confusion.

Binge use, where the user indulges in the drug in excess amounts in a short period of time has been reported, as well.